Regulation and directed inhibition of ECP production by human neutrophils.

Antonio Vega-Rioja,Pedro Chacón,Lourdes Fernández-Delgado,Bouchra Doukkali,Alberto Del Valle Rodríguez,James R Perkins,Juan A G Ranea, Leticia Dominguez-Cereijo, Beatriz María Pérez-Machuca,Ricardo Palacios,David Rodríguez,Javier Monteseirín,David Ribas-Pérez

Frontiers in immunology（2022）

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摘要

Our results suggest the molecular pathways involved in ECP production and potential therapeutic targets. We also provide a new method to evaluate disease severity in asthmatic patients based on the quantification of ECP production by peripheral neutrophils.

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关键词

ECP,IgE,allergen,allergy,asthma,cell signaling,cytokines,immunotherapy

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