ADAR1 promotes systemic sclerosis via modulating classic macrophage activation.

Frontiers in immunology（2022）

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摘要

Our studies reveal that ADAR1 promotes macrophage activation in the onset of SSc. Thus, targeting ADAR1 could be a potential novel therapeutic strategy for treating sclerosis formation.

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关键词

ADAR1,IL-1β,NF-κB,macrophage activation,systemic sclerosis

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