Analysis of Doberman Pinscher and Toy Poodle samples with targeted next-generation sequencing

A Arizmendi,G Rudd Garces,J A Crespi, L H Olivera,L S Barrientos,P Peral García,G Giovambattista

Gene（2023）

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摘要

•GBS is a powerful tool to study simultaneously traits and diseases in large samples.•GBS shows a high degree of accuracy.•Higher numbers of SNPs are needed to exclude a false progeny in inbred dogs.•Most genetic conditions were monomorphic in a specific breed or breed group.•Validation of GBS results for genetic disorders showed 94–100% concordance.

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关键词

Canis lupus familiaris,Targeted genotyping-by-sequencing,SNVs,Genetic disorders,Paternity test

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