The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia.

David O'Connor,Jonas Demeulemeester,Lucia Conde,Amy Kirkwood,Kent Fung,Foteini Papaleonidopoulou,Gianna Bloye,Nadine Farah,Sunniyat Rahman,Jeremy Hancock,Caroline Bateman,Sarah Inglott,Jon Mee,Javier Herrero,Peter Van Loo,Anthony V Moorman,Ajay Vora,Marc R Mansour

Blood（2023）

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摘要

The outcome of IF in T-ALL remains poor with current therapy. The lack of a unifying genetic driver suggests alternative approaches, particularly using immunotherapy, are urgently needed.

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关键词

clinicogenomic landscape,induction failure,t-cell

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