[Association of genomic instability of CDH1 gene with clinicopathological characteristics of gastric cancer].

Jitao Du,Xiangbin Wan, Huiliang Zhang, Jian Cao,Wen Zhao,Zhi Li

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics(2022)

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摘要
The genomic instability of the CDH1 gene is associated with the progression of gastric cancer. MSI at the D16S752 locus may be used as a molecular marker for early gastric cancer, while LOH at this locus mostly occurs in advanced gastric cancer and can be regarded as an effective indicators for malignancy evaluation and prognosis.
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关键词
cdh1 gene,gastric cancer,genomic instability
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