Platelet LGALS3BP as a Mediator of Myeloid Inflammation in Systemic Lupus Erythematosus.

Hanane El Bannoudi,MacIntosh Cornwell,Elliot Luttrell-Williams,Alexis Engel,Christina Rolling,Tessa J Barrett,Peter Izmirly,H Michael Belmont,Kelly Ruggles,Robert Clancy,Jill Buyon,Jeffrey S Berger

Arthritis & rheumatology (Hoboken, N.J.)（2022）

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摘要

Our results support that platelets act as potent effector cells that contribute to the pathogenesis of SLE by secreting proinflammatory LGALS3BP, which also represents a novel biomarker of SLE clinical activity.

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