Host happy hour: Phage cocktail targets IBD-associated microbes.
Cell host & microbe(2022)
摘要
Bacteriophage therapy is a promising strategy to treat bacterial infections and sculpt the microbiome. In a recent Cell paper, Federici et al. (2022) demonstrate that a Klebsiella pneumoniae phage cocktail can specifically remove pathobionts from the mouse gut. Safety and persistence of therapeutic phages were shown in a Phase 1 trial.
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关键词
microbes,ibd-associated
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