In vivo assembly drug delivery strategy based on ultra-small nanoparticles: Toward high drug permeation and accumulation for CNV treatment

Jingwen Yu,Yiming Wu,Qixuan Dai,Han Wu,Jintao Pan,Yuli Guo,Ke Yan,Huimin Zhu,Yi Mao,Sijie Lin,Wei Li,Gang Liu,Chengchao Chu

Chemical Engineering Journal（2022）

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摘要

•The two drugs combined delivery system could increase drug accumulation.•Few drugs residue in normal tissues.•The constructed CNV treatment possessed high anti-angiogenesis effect with excellent biosafety.

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关键词

Corneal neovascularization,Photothermal therapy,In vivo assembly,Biosecurity

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