The 18 kDa translocator protein is associated with microglia in the hippocampus of non-demented elderly subjects

Benjamin B. Tournier, Christophe Snoeijs,Stergios Tsartsalis,Quentin Amossé, Ramzi Farchoukh,Eniko Kövari,Kelly Ceyzériat,Philippe Millet

Aging Brain（2022）

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摘要

•TSPO is expressed in the hippocampus of non-demented elderly individuals.•TSPO is heterogeneously expressed in hippocampus subdivisions.•Glial cell reporters are heterogeneously expressed in hippocampus subdivisions.•Upregulation of TSPO occurs with age.•TSPO and IBA1 densities are correlated in the subiculum.

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TSPO,Alzheimer’s disease,Neuropathology,Non-demented

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The 18 kDa translocator protein is associated with microglia in the hippocampus of non-demented elderly subjects

The 18 kDa translocator protein is associated with microglia in the hippocampus of non-demented elderly subjects