Self-adhesive polyurethane via selective photo-polymerization for biocompatible epidermal soft sensor and thermal heater

•Polyurethane had adhesive property by laser-induced selective photo-polymerization.•Defective crosslinking networks enhanced the adhesive properties of polyurethane.•Biocompatibility of photo-polymerized polyurethane was confirmed through mouse test.•Self-adhesive soft sensor detected multiple human motions and sensitive bio-signals.•Attachable heater efficiently transferred heat to skin through conformal contact.