ID:16146 Two-Year Outcomes of an SCS System Capable of Multiple Neurostimulation Modalities: A Randomized Controlled Trial

Pre-clinical SCS studies have previosuly demonstated that neural activity, and in turn, perception of pain can be robustly modulated via the stimulation of different neuronal targets (e.g. dorsal Horn, dorsal column).1,2 Stimulation of multiple simultaneous targets via the dual use of sub- and supra-perception-based SCS modalities (i.e. combination therapy) may therefore be able to enhance pain relief outcomes. In support of this postulate, positive outcomes when using combination therapy in SCS-implanted patients have now been recently reported.3,4 Here, we will report long-term clinical outcomes out to 2-years follow-up derived from a prospective, randomized controlled trial (RCT) that evaluates the effectiveness of SCS using sub- and supra-perception modalities as a combination therapy for chronic pain.