The oncological multidimensional prognostic index is a promising decision-making tool: A real-world analysis in older patients with metastatic colorectal cancer

Letizia Procaccio,Francesca Bergamo,Maura Gatti,Benedetta Chiusole,Giuseppina Tierno,Eleonora Bergo,Francesca Daniel,Floriana Nappo,Giulia Maddalena,Cosimo Rasola,Giulia Barsotti,Maria C. De Grandis,Vittoria M. Piva,Mario D. Rizzato,Giuseppe Sergi,Antonella Brunello,Vittorina Zagonel,Sara Lonardi

European Journal of Cancer（2022）

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摘要

•Geriatric assessment in older cancer patients is recommended by current guidelines.•We analysed onco-MPI and comprehensive geriatric assessment in older mCRC patients.•The study demonstrated the prognostic role of onco-MPI and geriatric assessment.•Onco-MPI adds valuable information for proper management of older cancer patients.•Therapy was modulated by onco-MPI leading to survival benefit in all subgroups.

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关键词

Older patients,Metastatic colorectal cancer,Oncological multidimensional prognostic index,Comprehensive geriatric assessment,Real-world analysis,Chemotherapy intensity

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