Activation of the JAK1/STAT1 signaling pathway is associated with peroxiredoxin 6 expression levels in human epididymis epithelial cells.

Hui Shi,Xiaoyu Liu,Yanwei Wang,Haiyan Wang,Bochen Pan,Jianyuan Li

Folia histochemica et cytobiologica（2022）

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摘要

We found that reduced Prdx6 expression induced higher ROS levels in HEECs, which resulted in the activation of the IL-6 receptor and IFNγ expression to induce the JAK1/STAT1 signaling pathway.

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关键词

DGE,JAK1,Prdx6,RNAi,STAT1,human epididymis epithelial cells

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