Patterns of Daily Physical Movement, Chronic Inflammation, and Frailty Incidence.

Amal A Wanigatunga,Venus Chiu,Yurun Cai,Jacek K Urbanek,Christine M Mitchell,Edgar R Miller,Robert H Christenson,Heather Rebuck,Erin D Michos,Stephen P Juraschek,Jeremy Walston,Qian-Li Xue,Karen Bandeen-Roche,Lawrence J Appel,Jennifer A Schrack

Medicine and science in sports and exercise（2023）

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摘要

Among older adults who are either robust or prefrail, constricted patterns of daily physical activity (i.e., lower total activity minutes and counts, and higher activity fragmentation) were prospectively associated with higher risk of frailty but not modified by frailty-related chronic inflammation. Additional studies, particularly trials, are needed to understand if this association is causal.

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关键词

ACCELEROMETRY,IMMUNE FUNCTION,AGING,DEBILITY,OLDER ADULTS

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