Single-cell analysis reveals nanosecond pulsed electric field ablation induced myeloid cells remodeling in pancreatic cancer

Bioelectrochemistry(2022)

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摘要
•Changes in myeloid cells after nsPEF treatment using single-cell RNA sequencing.•Substantial transcriptional change seen in myeloid cell population.•Transcriptional change in modulation of the tumor microenvironment demonstrated.•Potential use in immune change analysis post-nsPEF treatment in pancreatic cancer.
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关键词
Tumor ablation,Single-cell RNA sequencing,Nanosecond pulsed electric field,Myeloid cells,Pancreatic cancer
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