Metal ions in cerebrospinal fluid: Associations with anxiety, depression, and insomnia among cigarette smokers.

Yuying Li,Fenzan Wu,Qingshuang Mu,Kewei Xu,Shizhuo Yang,Ping Wang,Yuyu Wu,Junnan Wu,Wei Wang,Hui Li,Li Chen,Fan Wang,Yanlong Liu

CNS neuroscience & therapeutics（2022）

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摘要

Cigarette smoking was indeed associated with depression and insomnia. Active smokers had significantly higher CSF levels of magnesium, zinc, iron, lead, lithium, and aluminum. Furthermore, CSF aluminum played a mediating role in the relationship between smoking and depression, which further confirmed its neurotoxicity.

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关键词

anxiety,cigarette smoking,depression,insomnia,metal ions

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