Identification of nine mutant genes and establishment of three prediction models of organ tropism metastases of non-small cell lung cancer.

Shuchen Chen,Wanyi Huang,Zhenzhen Liu,Meizi Jin,Jielin Li,Lihui Meng,Ting Li,Yuzhu Diao,Hong Gao,Chengyu Hong,Jian Zheng,Fei Li,Yue Zhang, Dan Bi,Lin Teng,Xiaoling Li

Cancer medicine（2023）

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摘要

Taken together, this study revealed nine mutant genes and smoking history associated with organ tropism metastases of NSCLC and provided three models for the prediction of metastatic organs. This study enables us to predict the organs to which non-small cell lung cancer metastasizes before it does develop.

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关键词

NGS,NSCLC,gene mutations,organ tropism metastases,prediction model,targeted therapy

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