Mechanical and Heat Hyperalgesia upon Withdrawal From Chronic Intermittent Ethanol Vapor Depends on Sex, Exposure Duration, and Blood Alcohol Concentration in Mice

•Male mice become more sensitive to mechanical stimuli than females after CIEV exposure.•Female mice become more sensitive to heat stimuli than males after CIEV exposure.•Female mice experience heat hyperalgesia during early acute withdrawal timepoints (1–5 hours).•Alcohol withdrawal-induced pain depends on sex, exposure length, and blood alcohol concentration.