Establishment of 6 pediatric rhabdomyosarcoma patient's derived xenograft models closely recapitulating patients' tumor characteristics.

Patrizia Gasparini,Michela Casanova,Giovanni Centonze,Cristina Borzi,Luca Bergamaschi,Paola Collini,Adele Testi,Stefano Chiaravalli,Maura Massimino,Gabriella Sozzi,Andrea Ferrari,Massimo Moro

Tumori（2022）

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摘要

Our findings increase the number of available RMS PDX models and strengthen the role of PDXs as useful preclinical tools for patients with unmet medical needs and to develop personalized therapies.

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关键词

Rhabdomyosarcoma,patient-derived xenografts,personalized therapy

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