APOE Is Associated With Serum Tau Following Uncomplicated Mild Traumatic Brain Injury.

Sara M Lippa,Rael T Lange,Clifton L Dalgard,Anthony R Soltis,Vivian A Guedes,Tracey A Brickell,Louis M French,Jessica Gill

Frontiers in neurology（2022）

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摘要

This study is the first to demonstrate APOE genotype is related to serum tau levels following a mTBI, extending prior findings to human serum following mTBI. In addition to higher serum tau levels in APOE e4 carriers, lower tau levels were observed in APOE e2 carriers, suggesting a possible protective effect.

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关键词

APOE,biomarkers,military,serum,tau,traumatic brain injury

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