Adjustable shunt-current intensity circuit and system for current conduction treatment of epilepsy

In this paper, we developed a shunt-current intensity self-adjustable closed-loop control circuit system for current conduction treatment in temporal lobe epilepsy. To examine the dose-response relationship between conductive intensity and therapeutic outcomes of current conduction treatment, the control system consists of neural signal recording module for high-speed data rate acquisition, signal amplification and pre-processing, current shunt module for current conduction, data transmission and control module for real-time data communication with the personal computer and on-off of current conduction. Multithread and queue software architecture was implemented to ensure real-time data transmission, display and analysis by LabVIEW software. Results indicate that the input noise of the system is less than 2 mu Vrms, signal frequency bandwidth range is 1 Hz similar to 10 kHz, and the shunt-current detection range is 0.1-3000 mu A with the accuracy of above 99.985%, meeting the requirements for the detection of neural electrophysiological signal and the research on the dose-response relationship between conductive intensity and therapeutic outcomes of electronic conduction treatment.