Plant In Situ Hi-C Experimental Protocol and Bioinformatic Analysis.

Francisco J Pérez-de Los Santos,Jesús Emiliano Sotelo-Fonseca,América Ramírez-Colmenero,Hans-Wilhelm Nützmann,Selene L Fernandez-Valverde,Katarzyna Oktaba

Methods in molecular biology (Clifton, N.J.)（2022）

引用 0|浏览6

暂无评分

摘要

Hi-C enables the characterization of the 0conformation of the genome in the three-dimensional nuclear space. This technique has revolutionized our ability to detect interactions between linearly distant genomic sites on a genome-wide scale. Here, we detail a protocol to carry out in situ Hi-C in plants and describe a straightforward bioinformatics pipeline for the analysis of such data, in particular for comparing samples from different organs or conditions.

查看译文

关键词

Arabidopsis,Bioinformatics,Chromosome conformation,Differential interactions,Hi-C,Sequencing

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要