Tumor-Associated Macrophages Promote Migration and Invasion via Modulating Il-6/STAT3 Signaling in Renal Cell Carcinoma

Shaojun Chen,Subo Qian,Lin Zhang,Xiuwu Pan,Fajun Qu,Yongjiang Yu,Xingang Cui,Haibo Shen

SSRN Electronic Journal（2022）

引用 3|浏览14

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摘要

•Tumor-associated macrophages (TAMs) infiltration is obviously increased and closely associated with tumor progression and poor prognosis in renal cell carcinoma (RCC).•TAMs significantly promoted RCC cells migration, invasion and epithelial-mesenchymal transition (EMT).•TAMs promote migration, invasion and EMT via activating IL-6/STAT3 signaling in RCC.

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关键词

TAMs,Renal cell carcinoma,IL-6,STAT3

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