Cover Feature: Structural Properties Dictating Selective Optotracer Detection of Staphylococcus aureus (ChemBioChem 11/2022)

The cover feature illustrates how the chemical design of optotracers can be used to enable selective detection of the Gram-positive cocci Staphylococcus aureus in monocultures and when present in cultures mixed with the Gram-negative rod Salmonella Enteritidis. This is the first study to show that the chemical structure and photophysics of the optotracer molecules, which are conformation-sensitive fluorescent tracer molecules detecting peptide- and carbohydrate-based biopolymers, can be used as key tunable characteristics for the development of optotracers for selective detection of bacterial species. More information can be found in the Full Paper by A. Richter-Dahlfors et al.