Increased Blood-Brain Barrier Permeability of the Thalamus Correlated With Symptom Severity and Brain Volume Alterations in Patients With Schizophrenia.

Yuqi Cheng, Ting Wang,Tianhao Zhang, Shu Yi,Shilun Zhao,Na Li,Yifan Yang,Fengrui Zhang,Lin Xu,Baoci Shan,Xiufeng Xu,Jian Xu

Biological psychiatry. Cognitive neuroscience and neuroimaging（2022）

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摘要

These results provide the first in vivo evidence of BBB disruption of thalamus in patients with schizophrenia and suggest that BBB dysfunction might contribute to the pathological brain structural alterations in schizophrenia.

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关键词

Blood-brain barrier,Brain volume,Schizophrenia,Thalamus

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