Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater

Marion Desdouits,David Polo,Cecile Le Mennec,Sofia Strubbia,Xi-Lei Zeng,Khalil Ettayebi,Robert L Atmar,Mary K Estes,Françoise S Le Guyader

EMERGING INFECTIOUS DISEASES（2022）

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摘要

Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such experiments can improve understanding of factors associated with norovirus survival in coastal waters and shellfish.

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France,Norovirus,United States,enteric infections,food safety,human intestinal enteroids,marine environment,persistence,stability,viruses

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