Methodological optimisation of intraoperative margin assessment using confocal microscopy

Introduction: Approximately 20-30% of women who undergo breast-conservation surgery (BCS) for cancer will require further surgery due to a close or involved margin with associated psychological morbidity and financial cost. This study focuses on the methodological technique for capturing intraoperative cellular level images using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland).