Multiple effects of polydopamine nanoparticles on Cu2+-mediated Alzheimer's β-amyloid aggregation

Xueqing Chen,Weiqun Gao,Yan Sun,Xiaoyan Dong

Chinese Journal of Chemical Engineering（2023）

引用 0|浏览9

暂无评分

摘要

•PDA NPs change Cu2+-mediated Aβ aggregation pathway by chelating Cu2+.•PDA NPs remove ROS and rescue damaged cells.•NIR photothermal effect of PDA NPs promotes degrading Aβ42-Cu2+ complexes.•PDA NPs reduce Aβ plaques and prolong the lifespan of AD nematodes.

查看译文

关键词

Protein,Aggregation,Nanoparticles,Photothermal therapy,Reactive oxygen species,Cu2+ chelator

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要