Development of a topical bacteriophage gel targeting Cutibacterium acnes for acne prone skin and results of a phase 1 cosmetic randomized clinical trial.

M Golembo, S Puttagunta, U Rappo, E Weinstock, R Engelstein, I Gahali-Sass, A Moses, E Kario, E Ben-Dor Cohen, J Nicenboim, H Ben David, K Sudakov,A Cohen, M Bassan,N B Zak

Skin health and disease（2022）

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摘要

Combined in silico and ex vivo approaches successfully predicted the observed safety and efficacy of targeting phage when these were topically administered in a well-controlled cosmetic clinical study.

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