Dynamics of the natural genesis of β-TCP/HAp phases in postnatal fishbones towards gold standard biocomposites for bone regeneration

Wilson Ricardo Weinand, José Adauto Cruz,Antonio Neto Medina, Walter Moreira Lima,Francielle Sato,Raquel da Silva Palacios,Mariana Sversut Gibin,Eduardo Azzolini Volnistem,Jaciele Marcia Rosso,Ivair Aparecido Santos,Jurandir Hillmann Rohling,Antonio Carlos Bento,Mauro Luciano Baesso,Camila Girotto da Silva, Erika Xavier Dos Santos,Douglas Bolzon Scatolim,Alessandro Gavazzoni,Alfredo Franco Queiroz,Mychelle Vianna Pereira Companhoni,Tania Ueda Nakamura,Luzmarina Hernandes,Taiana Gabriela Moretti Bonadio, Luis Carlos Moura Miranda

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2022）

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摘要

•Natural genesis of β-TCP/HAp phases was used for biocomposites development.•Postnatal fishbones were used towards gold standard biocomposites for implants.•The β-TCP and HAp phases were characterized by physicochemical methods.•In vivo test showed remarkable regenerative action of the bioceramics in alveolar bone.•A logistic model showed three stages of HAp natural formation with fish age and size.

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关键词

Biphasic calcium phosphate,β-tricalcium phosphate,Fishbone,Genesis of the β-TCP/HAp phases,Bone regeneration

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