Maternal and prenatal factors and age at thelarche in the LEGACY Girls Study cohort: implications for breast cancer risk.

Mandy Goldberg,Jasmine A McDonald,Lauren C Houghton,Irene L Andrulis, Julia A Knight,Angela R Bradbury,Lisa A Schwartz,Saundra S Buys,Caren J Frost,Mary B Daly,Esther M John,Theresa H M Keegan,Wendy K Chung,Ying Wei,Mary Beth Terry

International journal of epidemiology（2023）

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摘要

Earlier thelarche, a breast cancer risk factor, was associated with three potentially modifiable maternal risk factors-pre-pregnancy BMI, gestational weight gain and physical inactivity-in a cohort of girls enriched for BCFH.

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关键词

Puberty,birth length,birthweight,breast cancer family history,breast development,gestational weight gain,physical activity,pre-pregnancy BMI,thelarche

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