Cytotoxicity effects and biochemical investigation of novel tetrakis-phthalocyanines bearing 2-thiocytosine moieties with molecular docking studies

•Single crystal X-ray diffraction measurements of 3-(4-aminopyrimidin-2-ylthio) phthalonitrile (1).•Synthesis of novel water-soluble tetrakis-phthalocyanines bearing 2-thiocytosine moieties.•Biochemical investigation with molecular docking studies.•Cytotoxicity potential against human breast, colon, and prostate cancers.