Hierarchical Epidemic Model on Structured Population: Diffusion Patterns and Control Policies
COMPUTATION(2022)
摘要
In the current study, we define a hierarchical epidemic model that helps to describe the propagation of a pathogen in a clustered human population. The estimation of a novel coronavirus spreading worldwide leads to the idea of the hierarchical structure of the epidemic process. Thus, the propagation process is divided into three possible levels: a city, a country, and a worldwide. On each level, the pathogen propagation process is based on the susceptible-exposed-infected-recovered (SEIR) model. We thus formulate a modified transmission model of infected individuals between levels. The control of the pathogen's spread can be seen as an optimal control problem. A trade-off exists between the cost of active virus propagation and the design of appropriate quarantine measures. Each level of the hierarchy is defined by its network. A series of numerical experiments was conducted to corroborate the obtained results.
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关键词
epidemic process, compartment epidemic models, SIR model, optimal control
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