COVID-19 Incidence Among 6th-12th Grade Students by Vaccination Status

Coronavirus disease 2019 (COVID-19), school closures, and quarantines have had substantial impacts on students' health and education.1,2,3 Clinical trials have shown severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines to be safe and efficacious for adults, adolescents, and young children.4 However, in some areas, vaccine uptake has been low among children and adolescents, especially compared to uptake in adults.1 Additionally, real-world vaccine effectiveness data among adolescents and implications for in-person education are lacking. We investigated the impact of COVID-19 vaccination on SARS-CoV-2 incidence and within-school transmission in a cohort of 6th-12th grade students.