Shared genetic aetiology between childhood intelligence and longevity

Background Intelligence and longevity are phenotypically and genetically correlated. Whereas molecular genetic data has been used to show that adult intelligence is genetically correlated with longevity, no such analysis has examined the association between childhood intelligence and longevity. Method and Results Using genome wide association study data on childhood intelligence (n = 12,441) and on parental longevity (n = 389,166) we found a positive genetic correlation of rg = 0.35 (SE = 0.14, P = 0.01) between childhood intelligence and parental longevity. Conclusion These results add to the weight of evidence that the phenotypic link between childhood intelligence and longevity is, partly, accounted for by shared genetic aetiology. . CC-BY 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (which was not certified by peer review) The copyright holder for this preprint this version posted February 12, 2021. ; https://doi.org/10.1101/2021.02.10.21251491 doi: medRxiv preprint