Schizophrenia Imaging Signatures and Their Associations With Cognition, Psychopathology, and Genetics in the General Population.
The American journal of psychiatry(2022)
摘要
The authors successfully replicated two neuroanatomical signatures of schizophrenia and describe their prevalence in population-based samples of youths and adults. They further demonstrated distinct relationships of these signatures with psychosis symptoms, cognition, and genetic risk, potentially reflecting underlying neurobiological vulnerability.
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关键词
Genetics/Genomics,Machine Learning,Neuroanatomy,Neuroimaging,Polygenic Risk Scores,Schizophrenia Spectrum and Other Psychotic Disorders
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