Zinc and cadmium isotopic constraints on ore formation and mineral exploration in epithermal system: A reconnaissance study at the Keyue and Zhaxikang Sb–Pb–Zn–Ag deposits in southern Tibet

•SEDE genesis is most plausible for the first episode of mineralization in the Zhaxikang and Keyue deposits.•A genetic relationship must exist between the Zhaxikang and Keyue deposits.•The Zhaxikang and Keyue deposits have the same metal origins and experience similar ore formation and ore-forming fluid evolution.•Zn–Cd isotopes have the potential to apply in ore deposit research and mineral exploration.