br 3D Covalent Organic Frameworks with Interpenetrated pcbTopology Based on 8-Connected Cubic Nodes

The connectivity of building units for 3D covalent organic frameworks (COFs) has long been primarily 4 and 6,which have severely curtailed the structural diversity of 3D COFs. Here we demonstrate the successful design and synthesis of aporphyrin based, 8-connected building block with cubic configuration, which could be further reticulated into an unprecedentedinterpenetrated pcb topology by imine condensation with linear amine monomers. This study presents thefirst case of high-connectivity building units bearing 8-connected cubic nodes, thus greatly enriching the topological possibilities of 3D COFs.