Regioselective Halogen—Metal Exchange Reaction of 3-Substituted 1,2-Dibromo Arenes: The Synthesis of 2-Substituted 5-Bromobenzoic Acids.

Karsten Menzel,Lisa DiMichele,Paul M. Mills,Doug E. Frantz,Todd D. Nelson,Michael H. Kress

ChemInform（2006）

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摘要

Regioselective halogen-metal exchange reactions using isopropylmagnesium chloride were carried out on 3-substituted 1,2-dibromo arenes. Eleven examples are given.

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