Sex- and gender-related differences linked to SARS-CoV-2 infection among the participants in the web-based EPICOVID19 survey: the hormonal hypothesis

Federica Prinelli,Caterina Trevisan,Marianna Noale,Michela Franchini,Andrea Giacomelli,Liliana Cori,Nithiya Jesuthasan,Raffaele Antonelli Incalzi,Stefania Maggi,Fulvio Adorni

Maturitas（2022）

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摘要

•COVID-19 is characterized by marked sex and gender differences.•The role of sex hormones in SARS-CoV-2 infection is largely unknown.•Female sex and younger age were negatively associated with the severity of the disease in this study.•Older females seem to benefit from hormonal therapy against the SARS-CoV-2 infection.

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关键词

SARS-CoV-2,COVID-19,Sex,Gender,Hormone therapy,Nasopharyngeal swab testing,Infection severity,Web-based survey,Cross-sectional design

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