Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy

JOURNAL OF MOLECULAR CELL BIOLOGY(2022)

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摘要
Alzheimer's disease(AD),a neurodegen-erative disease,is identified as the most common cause of dementia(Goedert and Spillantini,2006).Typical symptoms of AD in neuropathology are closely associated with changes in synapses and neurons(Serrano-Pozo et al.,2011).
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关键词
synaptic degeneration,degeneration ad model,prefrontal cortex
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