Inhibition of mitochondrial fission alters neo-intimal hyperplasia via PI3K/Akt signaling in arteriovenous fistulas.

Vascular(2022)

引用 2|浏览15
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摘要
Our results suggest that inhibition of mitochondrial fission improves AVF patency by reducing wall thickening through the PI3K/Akt signaling pathway. Therefore, inhibition of mitochondrial fission has the clinical potential to improve AVF patency.
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关键词
PI3K/Akt,arteriovenous fistula,mitochondrial fission,neo-intimal hyperplasia,vascular smooth muscle cell
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