Prevalence and features of non-motor symptoms in Wilson’s disease

Gianluigi Rosario Palmieri,Giovanna De Michele,Margherita Matarazzo,Fabiola Di Dato,Sandra Perillo, Diletta Carmen Paola Dello Iacovo,Nunzia Cuomo,Chiara Pane,Cinzia Valeria Russo,Raffaele Iorio,Giuseppe De Michele,Anna De Rosa

Parkinsonism & Related Disorders（2022）

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摘要

•Wilson's Disease (WD) is mostly characterized by motor, psychiatric and cognitive symptoms.•We aimed to assess and characterize other non-motor symptoms (NMS), as affective, sleep, and autonomic disorders.•NMS are more severe and frequent in WD subjects than controls.

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