PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging.
Aging pathobiology and therapeutics（2021）
摘要
PathoClock and PhathoAge can be used to capture biological changes that predict BODN, a metric developed in humans, and compare multimorbidity across species. These mouse clocks are potential translational tools that could be used in aging intervention studies.
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关键词
Multimorbidity,aging,pathoAge,pathoClock,pathology,physioAge,physioClock,physiology
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