Dynamic Contrast-Enhanced MSCT in Preoperative cT Staging of Gastric Cancer

Junling Wang, Xia Li,Zhijie Zhang, Chao Jing,Jie Li

semanticscholar(2021)

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摘要
Purpose. To investigate the clinical value of double contrast-enhanced ultrasound (DCEUS) combined with dynamic contrastenhanced multislice CT (MSCT) in preoperative T staging of gastric cancer (GC). Methods. 206 patients with GC confirmed by preoperative gastroscopy from February 2019 to February 2021 were collected, all patients were examined by DCEUS and dynamic contrast-enhanced MSCT before operation, and the invasion depth (T staging) of GC was evaluated. 0e diagnosis results of DCEUS, dynamic contrast-enhanced MSCT, and combined diagnosis of DCEUS and MSCT methods (D&M method) were compared with the pathological staging results (gold standard). Results. 0e correct diagnosis rate of MSCT was 27.27% in T1 staging, 55.56% in T2 staging, 42.11% in T3 staging, 59.29% in T4 staging, and 55.34% in summation.0e correct diagnosis rate of DCEUS was 90.91% in T1 staging, 88.89% in T2 staging, 78.95% in T3 staging, 82.86% in T4 staging, and 83.98% in summation. 0e correct diagnosis rate of the D&Mmethod was 100.00% in T1 staging, 94.44% in T2 staging, 89.47% in T3 staging, 93.57% in T4 staging, and 93.69% in summation. 0e D&M method had higher correct diagnosis rate than MSCT or DCEUS alone, the correct diagnosis rate of the D&Mmethod in T1, T2, T3, and T4 staging was significantly higher than that of MSCT (P< 0.05).0e correct diagnosis rate of the D&Mmethod in T1, T3, and T4 was significantly higher than that of DCEUS (P< 0.05). 0e Youden index of preoperative T1, T2, T3, and T4 staging of GC by the D&M method was 99.49%, 94.44%, 84.13%, and 90.54%, respectively, and the Kappa values of these were 0.954, 0.966, 0.707, and 0.881, respectively. Conclusions. Dynamic contrastenhanced MSCT combined with DCEUS in the diagnosis of preoperative cT staging of GC has more validity, reliability, and revenue than the using of MSCT or DCEUS alone, which is an image evaluation method worthy of clinical promotion.
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