The Association of Estrogen Receptor Activity, Interferon Signaling, and MHC Class I Expression in Breast Cancer.

In Hye Song,Young-Ae Kim,Sun-Hee Heo,Won Seon Bang,Hye Seon Park, Yeon Ho Choi,Heejae Lee,Jeong-Han Seo,Youngjin Cho,Sung Wook Jung,Hee Jeong Kim,Sei Hyun Ahn,Hee Jin Lee,Gyungyub Gong

Cancer research and treatment（2022）

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摘要

MHC I expression and TIL levels might be affected by ER pathway modulation and IFN treatment. Further studies elucidating the mechanism of MHC I regulation could suggest a way to boost TIL influx in cancer in a clinical setting.

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关键词

Breast neoplasms,Estrogens,Interferons,Major histocompatibility complex,Receptors,Tumor-infiltrating lymphocytes

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