Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria.

A Raquel Esteves,Mário F Munoz-Pinto,Daniela Nunes-Costa,Emanuel Candeias,Diana F Silva,João D Magalhães,A Raquel Pereira-Santos,I Luisa Ferreira,Susana Alarico,Igor Tiago,Nuno Empadinhas,Sandra Morais Cardoso

Gut（2023）

引用 20|浏览12

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摘要

Taken together, our results demonstrate that chronic exposure to dietary BMAA can trigger a chain of events that recapitulate the evolution of the PD pathology from the gut to the brain, which is consistent with 'gut-first' PD.

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关键词

gut inflammation,intestinal bacteria,intestinal barrier function,neurobiology

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