Extremely low HDL and residual cardiovascular risk—a case report

Introduction Extremely low high-density lipoprotein cholesterol (HDL-C) is defined as levels below 20 mg/dL. Association between extremely low HDL-C levels may occur from artifactual, primary monogenic disorders or from secondary causes. We present a 55-year-old known diabetic male with extremely low HDL, in the absence of severe hypertriglyceridemia, with apolipoprotein A1 deficiency and presenting with acute myocardial infarction. Results Transradial angiography revealed triple vessel disease, for which the patient was medically managed and sent home in a stable condition and is presently on follow-up. Conclusion Such cases are infrequent and pose a diagnostic challenge.