Treatment Of Thrombotic Thrombocytopenic Purpura

Gennadii M. Galstyan,Alexei A. Maschan,Elizaveta E. Klebanova,Irina I. Kalinina

TERAPEVTICHESKII ARKHIV（2021）

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摘要

The review discusses approaches to treatment of congenital thrombotic thrombocytopenic purpura (TTP) or Upshaw-Schulman syndrome. In congenital TTP, plasma transfusions are sufficient. Such treatment options as plasma exchange, administration of clotting factor VIII concentrate, recombinant ADAMTS13, are also used. Separately discussed issues of management of patients with TTP during pregnancy, and pediatric patients with TTP.

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关键词

ADAMTS13, thrombotic thrombocytopenic purpura, Upshaw-Schulman syndrome, pregnancy, therapeutic plasma exchange, recombinant ADAMTS13

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