The 26th Annual Prostate Cancer Foundation Scientific Retreat Report

Background The 26th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24-26, 2019 in Carlsbad, CA. Methods The Annual PCF Scientific Retreat is a global scientific research conference that focuses on the most promising and interesting new research in the prostate cancer field, and topics arising from other fields that have the potential to impact and advance prostate cancer research and clinical care. Results The primary topic areas addressed at the 2019 PCF Retreat included: (i) new insights into prostate cancer biology and treatment; (ii) new drugs and drug targets in prostate cancer; (iii) advances in prostate cancer genomics; (iv) lessons from the multi-arm, multistage randomized phase 3 STAMPEDE trial; (v) advances in immunotherapy for prostate cancer; (vi) factors contributing to prostate cancer racial disparities; (vii) treatment-associated small-cell/neuroendocrine prostate cancer (t-SCNC); (viii) artificial intelligence and machine learning in cancer research and development; (ix) population science research on prostate cancer; and (x) prostate cancer research in the Department of Veterans Affairs. Conclusions This article reviews the presentations from the 2019 PCF Scientific Retreat. We hope that this knowledge will accelerate research leading to new understandings of prostate cancer biology and improve treatments for patients with prostate cancer.